Increase of HLA-DRB1*0408 and -DQB1*0301 in HLA-B27 positive reactive arthritis
نویسندگان
چکیده
منابع مشابه
Increase of HLA-DRB1*0408 and -DQB1*0301 in HLA-B27 positive reactive arthritis.
OBJECTIVE To study HLA class II association in reactive arthritis. METHODS 63 patients with reactive arthritis and 46 with rheumatoid arthritis were included in the study. HLA-DR alleles were determined by using a sequence specific PCR method. Oligonucleotide hybridisation was used for definition of DRB1*04 subtypes and DQB1 alleles. HLA-B27 was determined by standard microcytotoxity test or ...
متن کاملHLA-B27-associated reactive arthritis: pathogenetic and clinical considerations.
Current evidence supports the concept that reactive arthritis (ReA) is an immune-mediated synovitis resulting from slow bacterial infections and showing intra-articular persistence of viable, non-culturable bacteria and/or immunogenetic bacterial antigens synthesized by metabolically active bacteria residing in the joint and/or elsewhere in the body. The mechanisms that lead to the development ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1997
ISSN: 0003-4967
DOI: 10.1136/ard.56.1.37